ATRIAL CONDUCTION SLOWS IMMEDIATELY PRIOR TO HUMAN ATRIAL FIBRILLATION INITIATION
نویسندگان
چکیده
منابع مشابه
Observations on concealed conduction in atrial fibrillation.
The mechanism of the ventricular dysrhythmia associated with atrial fibrillation in isolated rabbit heart was studied by recording electrograms from right atrium and ventricle simultaneously with transmembrane action potentials recorded from single fibers within the A-V node and right bundle branch. In most experiments, the variation in ventricular cycle length during experimentally initiated a...
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from altered intrinsic SAN pacemaker function. Indeed, spontaneous action potential frequencies in SAN myocytes with CIO were reduced in association with decreased L-type Ca current (ICa,L) densities and positive (rightward) voltage shifts in ICa,L activation. Pacemaker current (If) was not affected by CIO. Because ICa,L in SAN myocytes (as well as in atrial and conducting system myocytes) acti...
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OBJECTIVES This study sought to characterize direction-dependent and coupling interval-dependent changes in left atrial conduction and electrogram morphology in uniformly classified patients with paroxysmal atrial fibrillation (AF) and normal bipolar voltage mapping. BACKGROUND Although AF classifications are based on arrhythmia duration, the clinical course, and treatment response vary betwe...
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Introduction Catheter ablation is effective in symptomatic, drug refractory atrial fibrillation and can result in cure but success rates vary significantly with recurrences ranging from 4086%. In the months following ablation, LA wall scarring on late gadolinium enhancement (LGE) is useful for determining the location and extent of injury and has been used to guide follow up ablation to 'close ...
متن کاملDirection-dependent conduction abnormalities in a canine model of atrial fibrillation due to chronic atrial dilatation.
Chronic rapid atrial pacing (RAP) leads to changes that perpetuate atrial fibrillation (AF). Chronic atrial dilatation due to mitral regurgitation (MR) also increases AF inducibility, but it is not clear whether the underlying mechanism is similar. Therefore, we have investigated atrial electrophysiology in a canine MR model (mitral valve avulsion, 1 mo) using high-resolution optical mapping an...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2011
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(11)60087-9